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research A Founder Mutation in the POMC 5′-UTR Causes Proopiomelanocortin Deficiency Through Splicing-Mediated Decrease of mRNA

4 citations , July 2022 in “The Journal of Clinical Endocrinology & Metabolism”

This study identified a novel homozygous mutation in the 5'-UTR of the POMC gene, suggesting a new molecular mechanism for the syndrome of adrenal insufficiency, obesity, and red hair.

research Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA

3 citations , February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine”

This study suggests that hair loss disorders like Marie Unna hereditary hypotrichosis may result from mutations that disrupt post-transcriptional regulation of HR protein expression by PCPB2 interacting with Hr mRNA.

research P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression

24 citations , December 2016 in “Stem Cell Research & Therapy”

This study found that P311 triggers transdifferentiation of epidermal stem cells into myofibroblast-like cells via TGFβ1/Smad signaling during wound healing.

research Association of single nucleotide polymorphisms in the RAB5B gene 3′UTR region with polycystic ovary syndrome in Chinese Han women

11 citations , April 2019 in “Bioscience Reports”

In this study, single nucleotide polymorphisms in the RAB5B gene were linked to an increased risk of polycystic ovary syndrome and associated with specific microRNA binding sites.

research Association of HSPA1B SNP rs6457452 with Alopecia Areata in the Korean Population

12 citations , December 2013 in “Immunological Investigations”

This study suggests that the 5’UTR SNP rs6457452 of HSPA1B may be associated with the onset of Alopecia Areata and reduced susceptibility in the Korean population.

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Learn

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learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Providers say SMP usually needs a touch-up every 1 to 5 years. It fades but does not fully disappear, and removal needs laser treatment that may be incomplete.

learn Hair Transplant

How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.
How much does a hair transplant cost? Hair transplant costs typically range from $1,000 to $25,000 depending on various factors.

learn Biopeptide-5

learn O-Cymen-5-Ol

learn Minoxidil

Minoxidil 2%, 5% and 10% which is better to use? In a randomized trial in men, 5% topical minoxidil produced more hair growth than 2%, and in one small trial 10% did not beat 5% and caused more irritation. No 10% product is approved in the US, and approved strengths differ by sex, so check the label for your product.

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Clinics

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Community Join

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community 5+ years deep on fin. Absolute life changer

40 upvotes 2 days ago

The user has been using finasteride for around six years, maintaining a full head of hair and feeling liberated from anxiety about hair loss. They did not pair it with minoxidil and experienced no side effects, taking 1mg every other day.

community 5% Min 0.1% Fin topical spray, 9 month progress. Can those baby hairs grow longer to even my hairline?

4 upvotes 1 week ago

A user shared their 9-month progress using a 5% Minoxidil and 0.1% Finasteride topical spray for hair loss, questioning if baby hairs can grow longer to even their hairline. Another user suggested that oral treatments might be necessary for significant hair loss, as topical treatments alone may not be effective.

community 5 months Update - Minoxidil + Finasterid - Norwood 7 Comeback?!

18 upvotes 1 week ago

The user started using oral finasteride and minoxidil for hair regrowth, experiencing some uneven and thinner hair growth. They plan to wait 12 months before considering a hair transplant and are hopeful for further improvement.

community 5 years on dutasteride + oral minoxidil (before and after pics)

18 upvotes 2 weeks ago

A 26-year-old male shared his 5-year experience using dutasteride and oral minoxidil for hair loss, reporting noticeable improvement and slower progression. Despite ongoing shedding, he is satisfied with the results, believing the regimen prevented more severe hair loss.

community 5 months on 0.5 Dutasturide + 2.5 Minoxidil

22 upvotes 2 weeks ago

The conversation discusses hair loss treatments, specifically using 0.5 Dutasteride and 2.5 Minoxidil. Users share experiences, noting mixed results and emphasizing the importance of overall health and lifestyle in hair regrowth.

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Experts

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