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Glossary2D cell culture

cells grown on flat surfaces for research purposes

2D cell culture, also known as two-dimensional cell culture, is a laboratory technique where cells are grown on a flat, typically plastic, surface such as a petri dish. This method allows researchers to study cell behavior, drug responses, and biological processes in a controlled environment, but it may not fully replicate the complex interactions found in a living organism.

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Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid

research Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid

November 2021 in “Research Square (Research Square)”

3D spheroid cultures of human hair follicle cells are better for hair growth research than 2D cultures, and they provide new insights into how hair growth treatments like minoxidil and TCQA work.

research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)

2 citations, June 2022 in “Cells”

3D cell cultures are better for testing hair growth treatments than 2D cultures.

research In This Issue

December 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.

research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods

35 citations, January 2020 in “Skin Pharmacology and Physiology”

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

research Novel In Vitro Culture Condition Improves the Stemness of Human Dermal Stem/Progenitor Cells

18 citations, November 2013 in “Molecules and Cells”

New culture method keeps human skin stem cells more stem-like.

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community 11mth daily 0.5mg oral finasteride

in Finasteride/Dutasteride 791 upvotes 5 days ago

The user experienced significant hair regrowth with 0.5mg oral finasteride daily, despite a minoxidil allergy, and reported no side effects. They also used a keto shampoo and were satisfied with the results.

community Are topicals with caffeine useful to promote hairgrowth?

in Research/Science 3 upvotes 6 months ago

The user is asking if caffeine topicals are effective for hair growth, noting they already use Minoxidil and finasteride. They are unsure if caffeine topicals are beneficial or a waste of money.

community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 634 upvotes 3 months ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community Hair Tattoo as a substitue to hair transplant

in Transplants 517 upvotes 1 year ago

A hair tattoo substitute for a hair transplant, which many people felt was not a good idea. Several treatments were suggested as alternatives, such as Scalp Micro Pigmentation (SMP) and wigs.

community 24M , been a month on minoxidil Finastride nizoral any difference ?

in Treatment 153 upvotes 2 years ago

A user who has been taking minoxidil, finasteride and nizoral for one month, asking if there is any difference in their hair loss; the responses suggest that some improvement may have been seen but it can be hard to tell with just one month of treatment.