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research Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways

October 2025 in “Cell Proliferation”

In laboratory research, investigators found that apoptotic vesicles from interleukin-10-treated fibroblasts promote wound healing and reduce fibrotic scarring by enhancing mitochondrial function, modulating collagen composition, and inhibiting the Hedgehog signalling pathway, offering potential for regenerative medicine applications.

research Cutaneous Squamous Cell Carcinoma of the Head and Neck: A Retrospective Analysis of Loco-Regional Recurrences and Survival Rates Over a Consecutive 10-Year Period

July 2024 in “Cureus”

This study retrospectively analyzed 945 patients with head and neck cSCC to identify risk factors for recurrences, reporting treatment modality, tumor characteristics, and patient factors such as immunosuppression as strong predictors for loco-regional recurrences.

research A novel model for designing and performing parietal whorl hair transplantation

December 2019 in “Journal of Cosmetic Dermatology”

In this study, researchers developed an innovative training model using oranges to practice designing the scalp's parietal whorl for hair transplantation. They reported that a density of 40-50 follicular units per cm² achieved better results, aiding surgeons in improving their technique.

research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition

3 citations , October 2021 in “PLoS ONE”

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

research Th1/Th2 PB balance and CD200 expression of patients with active severe alopecia areata

12 citations , April 2017 in “Experimental and Therapeutic Medicine”

This study found that patients with active severe alopecia areata exhibited decreased CD200 expression on T and B lymphocytes, which may be linked to an imbalance in Th1/Th2 immune equilibrium.

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community Back From The Dead( 1 Yr 5% Min 0.1% Fin)

in Progress Pictures 302 upvotes 1 year ago

The conversation is about a user who experienced significant hair recovery using 5% Minoxidil and 0.1% Finasteride, specifically with the Traya brand. The user emphasizes consistency and early treatment for effective results, noting improvements in hair volume and some side effects like dry scalp.

community How Often Should I Use a 1.0mm Dermaroller for Hair Growth?

in General 32 upvotes 1 year ago

The conversation discusses using a 1.0mm dermaroller for hair loss, with the user experiencing mild redness that subsided quickly. The user seeks advice on the frequency of dermaroller use.

community I am using topical minoxidil 5%+finasteride 0.1% solution since 8 months.

in Is this regrowth? 34 upvotes 10 months ago

A 42-year-old is using a topical solution with 5% minoxidil and 0.1% finasteride, along with weekly microneedling, for hair regrowth without side effects. The product used is Tugain for men by Cipla, an Indian brand.

community Do essential oils help promote hair regrowth along the hairline combined with 1.0 mm dermarolling? (I am on finasteride)

6 upvotes 7 years ago

Essential oils combined with dermarolling may not significantly promote hair regrowth along the hairline. Minoxidil and finasteride are more commonly used, with minoxidil potentially causing initial hair shedding.

community Why are we using 1.5mm for microneedling? Evidence says we don't need to.

39 upvotes 4 months ago

Shorter microneedle lengths, like 0.5mm, may be more effective and safer for hair regrowth than longer ones, such as 1.5mm, which can cause more pain and risk. Users report success with various regimens, including minoxidil, finasteride, and other topicals, alongside microneedling.

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learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn 1,2-Hexanediol

learn Tripeptide-1

learn Biotinoyl tripeptide 1

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learn Ketoconazole

Is there a difference between 1% and 2% ketoconazole? The documented differences are strength and supply: 1% ketoconazole shampoo is sold over the counter while 2% is usually prescription-only, and almost all of the trial evidence — including a 2015 Cochrane review — was gathered on the 2% shampoo rather than in a head-to-head comparison of the two strengths.

learn Biotin

Biotin, Biotinyl-GHK, biotinoyl-tripeptide-1… are they not the same? Biotin, Biotinyl-GHK, and Biotinoyl-Tripeptide-1 are different compounds with distinct functions.

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