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community Thank to this community - started in may 2022. 5 percent min 2 times daily - 0.5 fin daily - 1.5 mm dermaroller weekly. Started with 1mm deramaroller at start.

in Progress Pictures 77 upvotes 2 years ago

A user shared their hair loss treatment progress, using 5% Minoxidil twice daily, 0.5 mg Finasteride daily, and a 1.5 mm dermaroller weekly. They started with a 1 mm dermaroller in May 2022.

community Dutasteride 0.5 mg/day lowers scalp DHT levels by only 50% (but 2.5 mg/day lowers scalp DHT by 80%).

in Finasteride/Dutasteride 132 upvotes 1 year ago

Dutasteride at 2.5 mg/day reduces scalp DHT by 80%, while 0.5 mg/day reduces it by 50%, with minimal difference in side effects. Users often combine it with finasteride, RU58841, and minoxidil for better hair loss management, though side effects like dry skin and pimples are noted.

community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

in Research/Science 63 upvotes 2 years ago

The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

community Dry flakes from topical fin use

in Finasteride/Dutasteride 2 upvotes 1 year ago

The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.

community How many guys on here are doing the low dose topical finasteride (solo without minox)?

25 upvotes 4 years ago

User discusses using low dose topical finasteride without minoxidil for hair loss. Another user shares their experience with homemade 0.025% finasteride topical, shedding, and microneedling.

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Research

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research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia

65 citations , October 1999 in “Journal of The American Academy of Dermatology”

In this study, finasteride doses as low as 0.2 mg per day significantly reduced both scalp skin and serum DHT levels in men with androgenetic alopecia.

research A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia

43 citations , July 2018 in “Journal of The European Academy of Dermatology and Venereology”

This study found that a topical solution combining 0.25% finasteride with 3% minoxidil significantly improved hair growth, as measured by hair density, diameter, and global assessment, in men with androgenetic alopecia, compared to 3% minoxidil alone, over 24 weeks without systemic adverse effects reported.

research Comparative efficacy of topical finasteride (0.25%) in combination with minoxidil (5%) against 5% minoxidil or 0.25% finasteride alone in male androgenetic alopecia: A pilot, randomized open-label study

March 2023 in “International Journal of Trichology”

This study found that a combination of topical 5% minoxidil and 0.25% finasteride was more effective at improving hair density and satisfaction in men with androgenetic alopecia than either treatment alone over 24 weeks.

research Application of 2-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazol (NBDCL) for Spectrophotometric Determination of Finasteride in Pharmaceutical Formulation

January 2016 in “International journal of advanced research in chemical sciences”

This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.

research Book Review Pediatric Endocrinology: A Practical Clinical Guide (Contemporary Endocrinology.) Edited by Sally Radovick and Margaret H. MacGillivray. 582 pp., illustrated. Totowa, N.J., Humana, 2003. $165. 0-89603-946-3

February 2004 in “The New England Journal of Medicine”

The book is a comprehensive and current guide on hair disorders, with minor flaws.

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Learn

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learn Overview

learn Finasteride

Is finasteride safe? Studies report that most men tolerate finasteride 1 mg, but case series, regulatory labelling and patient reports describe sexual, mood and cognitive effects that some say persisted after stopping, and how often that happens is not established. It is a prescription-only medicine and is contraindicated in pregnancy.
Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only and carries a pregnancy contraindication.

learn Dutasteride

Heavy duty finasteride that comes with higher risks

Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.
Dutasteride: Correct Dosage and Administration The standard dosage of dutasteride is 0.5 mg once daily.

learn Saw Palmetto

a natural and far less effective alternative to Finasteride

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Experts

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