Enhanced Clinical Outcomes and Treatment Adherence in Patients Using Compounded Topical Minoxidil to Treat Androgenetic and Traction Alopecia

    August 2025 in “ PubMed ”
    James H. Wyche, Crystal Aguh
    Studysummary This study found that compounded topical minoxidil was associated with higher adherence, fewer side effects, and more clinical improvement in Black women compared to over-the-counter minoxidil.
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    Research cited in this study 7

    1. Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men Cureus · 2023
    2. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    3. Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia Dermatology and therapy · 2023
    4. Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit? Clinical and Experimental Dermatology · 2022
    5. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    6. Off-Label Use of Topical Minoxidil in Alopecia: A Review American Journal of Clinical Dermatology · 2019
    7. Hair Breakage in Patients of African Descent: Role of Dermoscopy Skin appendage disorders · 2015

    Related research 2

    1. Contact Dermatitis Caused by Topical Minoxidil: Allergy or Just Irritation Acta Dermato Venereologica · 2025
    2. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023