Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

    July 2018 in “ Analytical sciences
    Kenichi Ohno, Tomomi Hasegawa, Tomomi Tamura, Haruka Utsumi, Kouwa Yamashita
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    Studysummary This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
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