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Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

8 citations , July 2018 in “Analytical sciences”

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

26 citations , October 2016 in “Biomolecules & Therapeutics”

This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.

research Effects of testosterone on mean arterial pressure and aquaporin (AQP)-1, 2, 3, 4, 6 and 7 expressions in the kidney of orchidectomized, adult male Sprague-Dawley rats

9 citations , January 2017 in “Archives of biochemistry and biophysics”

In this study, testosterone was reported to increase aquaporin levels and water reabsorption in the kidneys of male rats, potentially leading to higher blood pressure, with effects mitigated by flutamide and finasteride.

research Different levels of EGF, VEGF, IL‐6, MCP‐1, MCP‐3, IP‐10, Eotaxin and MIP‐1α in the adipose‐derived stem cell secretome in androgenetic alopecia

1 citations , February 2022 in “Experimental Dermatology”

This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.

research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin and MIP-1𝛼 in Adipose Derived Stem Cells (ADSCs) Secretome in Androgenetic Alopecia

January 2021

This study found that adipose derived stem cells in areas of alopecia in patients with androgenetic alopecia showed different levels of various signaling proteins compared to other scalp and periumbilical regions.

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Community Join

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community 36 YOM - 4 month results on meds

62 upvotes 1 week ago

A 36-year-old man has been using 1 mg oral finasteride and 5% topical minoxidil for 4 months, with plans for a hair transplant in a year or two. He reports slight scalp irritation from minoxidil, which resolved after switching brands, and has started microneedling to enhance results.

community 36 year old. 18month moxidil and fin.

in Progress Pictures 732 upvotes 1 year ago

A 36-year-old has been using 1mg oral finasteride daily and minoxidil foam twice daily for 18 months, experiencing significant hair regrowth with no side effects. Initial shedding occurred, but noticeable improvements began around 11 months, with major changes by 16 months.

community 3 years and 6 month Progress 1mg Fin Only zero Min or anything else

in Progress Pictures 258 upvotes 9 months ago

A user reported significant hair regrowth using only 1mg finasteride daily over 3.5 years, with no side effects. They stressed patience and consistency, seeing noticeable results after two years.

community .3% Fin (3mo) & .6% Minox (10mo) Topical results.

in Is this regrowth? 12 upvotes 1 year ago

The user is experiencing hair regrowth using topical 0.3% finasteride and 6% minoxidil, with no side effects noted. They are considering switching to oral treatments if progress stalls, but are currently satisfied with the results.

community Progress: 6 months on minox. 1 month of microneedling. 3 weeks on fin

in Progress Pictures 76 upvotes 1 year ago

The user experienced hair improvement using minoxidil, microneedling, and finasteride, with noticeable progress at the temples. They attribute most gains to minoxidil and plan to continue treatments, noting no significant side effects except increased libido.

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Learn

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learn Omega 3

Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.

learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
How many sessions will I need for a hair transplant? Providers give different answers, and the number is decided at consultation: some clinics quote courses of 3 to 6 sessions, but that pattern belongs to non-surgical treatments rather than to surgery. Ask your surgeon how many procedures your own case would need and how far apart they would be.
How many grafts can be transplanted in one session of a hair transplant? Typically, 1,000 to 6,000 grafts can be transplanted in one session.
All 4 questions on Hair Transplant →

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