Expression of Type I Hair Keratins in Follicular Tumors

May 2001 in “ British Journal of Dermatology ”

B. Cribier, Bernard Peltre, Lutz Langbein, Hermelita Winter, J. Schweizer, E Grosshans

type I hair keratins follicular tumors pilomatrixomas shadow cells hair matrix

Studysummary This study suggests that pilomatrixomas' maturation towards areas of shadow cells is linked to a gradual loss of differentiation-specific hair keratins, supporting a hair matrix origin for the tumor.

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research Immunohistochemical Localization of Cytokeratins and Involucrin in Calcifying Epithelioma: Comparative Studies with Normal Skin

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research Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation

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research Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype

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research The Catalog of Human Hair Keratins

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This study establishes a catalog of human type I hair keratins and identifies their specific roles and expression patterns during hair differentiation and growth in scalp follicles.

WNT Signaling in the Control of Hair Growth and Structure

Expression of Type I Hair Keratins in Follicular Tumors

Research cited in this study

research Immunohistochemical Localization of Cytokeratins and Involucrin in Calcifying Epithelioma: Comparative Studies with Normal Skin

research Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain

research Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation

research Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype

research The Catalog of Human Hair Keratins

research WNT Signaling in the Control of Hair Growth and Structure

research Spiny Keratoderma: A Demonstration of Hair Keratin and Hair Type Keratinization

research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle

research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes

research Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix

research Sequence Data and Chromosomal Localization of Human Type I and Type II Hair Keratin Genes