TLDR Valproic acid can cause hair loss, but information on hair color change is not detailed.
The document discusses valproic acid (VPA), a commonly prescribed antiepileptic drug, and its side effects, specifically noting that reversible alopecia or hair loss is among the potential adverse effects associated with VPA therapy. However, the document does not provide specific data or study results regarding the incidence, severity, or mechanisms of the hair color change induced by VPA, nor does it mention the number of individuals affected. Therefore, while it acknowledges hair loss as a side effect of VPA, the document lacks detailed information to provide a comprehensive summary of the issue as it pertains to hair color change.
11 citations,
January 2018 in “International journal of trichology” Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.
13 citations,
April 2019 in “Seizure” Valproic acid increases the risk of hair loss more than other drugs, especially in migraine patients, and lamotrigine may be a safer alternative.
2 citations,
April 2017 in “Asian Journal of Psychiatry” Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
18 citations,
January 1999 in “CNS Drugs” Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.
4 citations,
January 2019 in “PubMed” Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.
26 citations,
November 2016 in “European Journal of Clinical Pharmacology” Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
