External Validation of PCOS Questionnaire in Assessing Quality of Life in Women with PCOS Based on Lifestyle Changes with Therapeutic Measures Like Oral Contraceptive Pills and Metformin

December 2017 in “ Journal of Medical Science And clinical Research ”

Priyanka Routray

TLDR The PCOS questionnaire is valid for Indian women, but metformin doesn't significantly improve symptoms beyond oral contraceptives.

This study aimed to validate the PCOS questionnaire in assessing the quality of life in women with PCOS undergoing lifestyle changes and treatment with oral contraceptive pills, with or without metformin. Conducted with 50 participants, the study found that the combination of metformin and OC pills significantly improved menstrual irregularities and hirsutism, but did not significantly affect symptoms related to being overweight or psychological and emotional conditions. The study concluded that the PCOS questionnaire was validated for the Indian population, but metformin did not show a significant additional effect on symptom improvement, possibly due to the small sample size or short duration of the study.

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Effect of Metformin Using 2-Hour Postload Insulin for Measuring Insulin Resistance in Taiwanese Women with Polycystic Ovary Syndrome

research Effect of Metformin Using 2-Hour Postload Insulin for Measuring Insulin Resistance in Taiwanese Women with Polycystic Ovary Syndrome

6 citations , April 2016 in “Journal of the Formosan Medical Association”

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.

research Development of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire

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research Health-Related Quality of Life in Women with Polycystic Ovary Syndrome: A Comparison with the General Population Using the Polycystic Ovary Syndrome Questionnaire and the Short Form-36

167 citations , January 2006 in “Gynecological Endocrinology”

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Health Care-Related Economic Burden of Polycystic Ovary Syndrome During the Reproductive Life Span