Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells

    April 2022 in “ International Journal of Molecular Sciences ”
    Mei Li, Jiaojiao Zheng, Tian Wu … Wei Cheng
    Studysummary This study found that TRPV4 activation induced massive exocytosis and cellular changes associated with ferroptosis in melanoma cells, highlighting a potential role for TRPV4 in mediating these processes.
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    Research cited in this study 1

    1. Transient Stimulation of TRPV4-Expressing Keratinocytes Promotes Hair Follicle Regeneration in Mice British Journal of Pharmacology · 2020

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    2. Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells International Journal of Molecular Sciences · 2022