Trichoscopy and LC-OCT Findings in Sonidegib-Induced Alopecia in Patients with Advanced Basal Cell Carcinoma

September 2024 in “ Dermatology Reports ”

Irina Ciobotariu, Gerardo Palmisano, Giacomo Caldarola, Alfredo Piccerillo, F. Tassone, Simone Cappilli, Alessandro Di Stefani, Ketty Peris

sonidegib Hedgehog pathway inhibitor alopecia trichoscopy LC-OCT yellow dots black dots exclamation mark hairs broken hairs follicular spaces follicular ostia cadaverized hair

Studysummary In this study, 45 patients with advanced basal cell carcinoma treated with the medication sonidegib experienced a 24% incidence of alopecia, with detailed trichoscopic and LC-OCT examination revealing specific hair changes, suggesting LC-OCT might help identify early signs of alopecia from sonidegib use.

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