Transcutol containing vesicles for topical delivery of minoxidil
March 2011
in “Journal of Drug Targeting”
TLDR Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
The study investigated the use of Transcutol-containing vesicles for the topical delivery of minoxidil. The results showed that the vesicles improved the skin penetration of minoxidil and increased its efficacy in promoting hair growth. The study suggests that transcutol-containing vesicles could be a promising approach for topical delivery of minoxidil for the treatment of hair loss. The vesicles were found to be stable and had good entrapment efficiency. However, the concentration of Transcutol affected the viscoelastic behavior of the vesicles and their ability to interact with the lipidic bilayer. Further research is needed to optimize the formulation of PEVs for the effective delivery of minoxidil.
View this study on tandfonline.com →
Cited in this study
research Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil
PEVs improve minoxidil skin penetration, increasing hair growth.
research Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery
Niosomes improve minoxidil skin delivery for hair loss treatment.
research Liposomes and niosomes as potential carriers for dermal delivery of minoxidil
Liposomes better deliver minoxidil for hair loss treatment than niosomes.
research Effect of ethosomal minoxidil on dermal delivery and hair cycle of C57BL/6 mice
Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.
research Male androgenetic alopecia (Part II)
Finasteride effectively treats male hair loss, increasing length and thickness.
research Minoxidil: mechanisms of action on hair growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men
5% minoxidil works better for hair growth and density, with minor irritation.
research Allergic contact dermatitis to topical minoxidil solution: Etiology and treatment
Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
research Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion
More ethanol increases minoxidil delivery, but too much lowers efficiency.
Related
research Transcutol containing vesicles for topical delivery of minoxidil
Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
research Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil
PEVs improve minoxidil skin penetration, increasing hair growth.
research Liposomes and niosomes as potential carriers for dermal delivery of minoxidil
Liposomes better deliver minoxidil for hair loss treatment than niosomes.