TLDR Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
The article discusses allergic contact dermatitis caused by topical minoxidil solution, a treatment for hair loss. Propylene glycol, a solvent used in the preparation of minoxidil, is the most common allergen causing contact dermatitis. Patients who are allergic to propylene glycol can be given alternative solvents such as butylene glycol, glycerin, and polysorbate. However, patients who are allergic to minoxidil are no longer candidates for the topical treatment of their alopecia with minoxidil. Systemic androgen modulators provide an alternate treatment option for some of these patients.
115 citations,
November 1999 in “Journal of The American Academy of Dermatology” Minoxidil increases hair weight and count temporarily in men with hair loss.
17 citations,
May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
23 citations,
December 1995 in “Archives of Dermatology” Combination therapy improves hair growth in advanced hair loss.
32 citations,
May 1995 in “Contact Dermatitis” Minoxidil can cause allergic reactions, but testing helps identify the cause.
13 citations,
January 1988 in “Contact Dermatitis” Some patients using Minoxidil for baldness developed allergic skin reactions.
14 citations,
July 1987 in “Contact Dermatitis” A small percentage of minoxidil users may develop an allergic skin reaction.
14 citations,
July 1987 in “Contact Dermatitis” Minoxidil can cause allergic skin reactions in some users.
29 citations,
August 1985 in “Contact Dermatitis” Minoxidil can cause allergic reactions like burning, itching, and red bumps.
38 citations,
June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
123 citations,
February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
14 citations,
July 1987 in “Contact Dermatitis” Minoxidil can cause allergic skin reactions in some users.
