Topical Finasteride Combined With Minoxidil For Androgenetic Alopecia: An Updated Systematic Review And Meta-Analysis

    September 2025 in “ Journal of the American Academy of Dermatology ”
    Carolina Mira Dilly de Medeiros, A. Vieira, Ana Carolina Ventura de Santana de Jesus, Isabelle Albuquerque Reis, Letícia Hanna Moura da Silva Gattas Graciolli, Yasmin da Silva Moura, Beatriz Ximenes Mendes, Anelise Poluboiarinov Cappellaro, Luiz V. Rosa, Adélio Mendes
    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

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    Studysummary Combining topical finasteride with minoxidil significantly improves hair density in treating hair loss.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This updated systematic review and meta-analysis investigates the efficacy of combining topical finasteride with minoxidil for treating androgenetic alopecia (AGA), the most common form of hair loss in adults. The study addresses the limitations of previous analyses by focusing on hair density outcomes rather than just Global Photographic Assessment (GPA). The findings suggest that the combination treatment significantly improves hair density compared to either treatment alone, providing a more effective option for individuals suffering from AGA. The study emphasizes the potential benefits of this combined approach, although the exact number of participants involved in the analysis is not specified in the summary provided.
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