TLDR Tissue engineering improves burn scar reconstruction by using skin substitutes and replacing damaged tissues.
The document reviewed advancements in tissue engineering for burn scar reconstruction, highlighting the increasing survival rates of severe burn patients and the subsequent need for effective coverage of large burn areas. It discussed the development and clinical effectiveness of skin substitutes, as well as the replacement of subcutaneous fat tissue and cartilage, in providing permanent burn wound coverage and aiding reconstructive burn surgery. The review aimed to address the challenges faced by patients dealing with burn scar sequelae and the necessity for multiple reconstructions.
31 citations
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December 2014 in “Advances in Clinical and Experimental Medicine” Stem cells could improve plastic surgery but are not widely used due to cost and safety concerns.
39 citations
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September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
26 citations
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February 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Technique effectively treats deformities, achieves re-pigmentation, and releases scar contractures.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
3 citations
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March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
1 citations
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February 2023 in “International Journal of Molecular Sciences” The fascial layer is a promising new target for wound healing treatments using biomaterials.
November 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
November 2024 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.