The Use of Cyproterone Acetate/Ethinyl Estradiol in Hyperandrogenic Skin Symptoms: A Review

    Johannes Bitzer, Thomas Römer, Agnaldo Lopes da Silva Filho
    Studysummary This review highlights that Cyproterone acetate combined with ethinylestradiol is highly effective for treating severe acne and hirsutism in women with hyperandrogenism, and it also provides benefits for cycle control and mood improvement, according to the analysis of 78 studies.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Interventions for Hirsutism (Excluding Laser and Photoepilation Therapy Alone) Cochrane library · 2015
    2. Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group Fertility and sterility · 2011
    3. An Open Randomized Comparative Study of an Oral Contraceptive Containing Ethinyl Estradiol and Cyproterone Acetate with and without the GnRH Analogue Goserelin in the Long-Term Treatment of Hirsutism Gynecologic and obstetric investigation · 2010
    4. Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism Acta Obstetricia et Gynecologica Scandinavica · 2010
    5. The Antiandrogen Cyproterone Acetate: Discovery, Chemistry, Basic Pharmacology, Clinical Use and Tool in Basic Research Experimental and Clinical Endocrinology & Diabetes · 2009
    6. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    7. Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2003
    8. A Comparison of the Relative Efficacy of Antiandrogens for the Treatment of Acne in Hyperandrogenic Women Clinical Endocrinology · 2002
    9. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2001
    10. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2000
    11. The SAHA Syndrome: Overview and Classification Hormone Research in Paediatrics · 2000
    12. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999
    13. Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission Human reproduction · 1997
    14. Cyproterone Acetate for Severe Hirsutism: Results of a Double-Blind Dose-Ranging Study Clinical endocrinology · 1991

    Related research 2

    1. Diagnosis and Treatment of Polycystic Ovary Syndrome: A Comparative Review International journal of pharmaceutical sciences review and research · 2022
    2. The Use of Cyproterone Acetate/Ethinyl Estradiol in Hyperandrogenic Skin Symptoms: A Review The European Journal of Contraception & Reproductive Health Care · 2017