The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers

This document summarizes various studies that examined the pharmacokinetics of minoxidil in healthy volunteers. The studies found that minoxidil is quickly absorbed and eliminated from the body, with a half-life of around 4 hours. Higher doses of minoxidil led to higher levels in the blood and longer times for the body to eliminate it. The drug had little effect on blood pressure in people with normal blood pressure, but higher doses did affect pulse rate. The studies provide important information for the safe and effective use of minoxidil in treating hair loss.