The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus
September 1990
in “
Veterinary Dermatology
”
orf virus skin responses primary infection secondary infection clinical changes histopathological changes cellular immune response fibrocyte proliferation epidermal cell proliferation new epidermis neutrophils basophils mast cells degranulation erythema dendritic cells lymphocytes epithelial repair processes skin responses primary infection secondary infection clinical changes histopathological changes immune response fibrocyte proliferation epidermal cell proliferation new epidermis neutrophils basophils mast cells degranulation erythema dendritic cells lymphocytes epithelial repair
Studysummary This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.
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