Tertiary Hypothyroidism in a Dog

    February 2007 in “ Irish Veterinary Journal ”
    Robert E. Shiel, Els Acke, Antonella Puggioni, Joseph P. Cassidy, Carmel T. Mooney
    TLDR A dog with a pituitary tumor developed tertiary hypothyroidism, improved with treatment, but was later euthanized due to neurological issues.
    A 9-year-old male Labrador was diagnosed with tertiary hypothyroidism, a condition not previously reported in dogs, following treatment for pituitary-dependent hyperadrenocorticism. The dog exhibited symptoms such as weight gain, seborrhoea, and alopecia, with tests showing low thyroxine levels and a pituitary mass. Levothyroxine treatment improved dermatological issues and cholesterol levels, but the dog was euthanized due to neurological symptoms caused by a pituitary adenoma affecting the hypothalamus. This case highlighted the diagnostic challenges of central hypothyroidism and the importance of distinguishing between secondary and tertiary forms.
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