Tertiary Hypothyroidism in a Dog

    February 2007 in “ Irish Veterinary Journal
    Robert E. Shiel, Els Acke, Antonella Puggioni, Joseph P. Cassidy, Carmel T. Mooney
    Studysummary This study reported the first known case of tertiary hypothyroidism in a dog, diagnosed after a Labrador treated for hyperadrenocorticism presented with related symptoms and an MRI-revealed pituitary mass. Our plain-language summary of this paper — not a Tressless recommendation.
    A 9-year-old male Labrador was diagnosed with tertiary hypothyroidism, a condition not previously reported in dogs, following treatment for pituitary-dependent hyperadrenocorticism. The dog exhibited symptoms such as weight gain, seborrhoea, and alopecia, with tests showing low thyroxine levels and a pituitary mass. Levothyroxine treatment improved dermatological issues and cholesterol levels, but the dog was euthanized due to neurological symptoms caused by a pituitary adenoma affecting the hypothalamus. This case highlighted the diagnostic challenges of central hypothyroidism and the importance of distinguishing between secondary and tertiary forms.
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