Sulfation of minoxidil by human platelet sulfotransferase
November 1987
in “Clinica Chimica Acta”
TLDR Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
This study found that human platelets can convert minoxidil to minoxidil sulfate, which is essential for its vasodilator activity. The researchers also discovered inter-subject variations in sulfotransferase activity. However, the significance of platelet sulfotransferase in the pharmacologic action of minoxidil is difficult to assess, as the liver is recognized as the major site of sulfation.
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research Sulfation of minoxidil by liver sulfotransferase
Liver enzyme helps minoxidil work better for blood vessel relaxation.
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research Sulfation of minoxidil by human platelet sulfotransferase
Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.
research Sulfation of minoxidil by liver sulfotransferase
Liver enzyme helps minoxidil work better for blood vessel relaxation.