Sublingual Minoxidil 5 mg Versus Oral Minoxidil 5 mg for Male Androgenetic Alopecia: A Double-Blind Randomized Clinical Trial

    Baltazar Dias Sanabria, Hélio Amante Miot, Rodney Sinclair … Paulo Müller Ramos
    Studysummary This study found that both sublingual and oral minoxidil at 5 mg per day increased hair density similarly in men with androgenetic alopecia over 24 weeks, but sublingual administration was associated with fewer palpitations.
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    Research cited in this study 9

    1. Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2024
    2. Oral Minoxidil Versus Topical Minoxidil for Male Androgenetic Alopecia JAMA dermatology · 2024
    3. Oral Minoxidil For Hair Loss: Update And Perspectives Hair transplant forum international · 2023
    4. Sublingual Minoxidil for the Treatment of Male and Female Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase 1B Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    5. Adverse Effects of Low-Dose Oral Minoxidil for Androgenetic Alopecia in 435 Patients Journal of The American Academy of Dermatology · 2020
    6. Minoxidil Sulfotransferase Enzyme (SULT1A1) Genetic Variants Predict Response to Oral Minoxidil Treatment for Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2020
    7. Treatment of Male and Female Pattern Hair Loss with Sublingual Minoxidil: A Retrospective Case-Series of 64 Patients Journal of The European Academy of Dermatology and Venereology · 2020
    8. Oral Minoxidil Bio-Activation by Hair Follicle Outer Root Sheath Cell Sulfotransferase Enzymes Predicts Clinical Efficacy in Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2019
    9. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990

    Related research 6

    1. Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia International Journal of Pharmaceutical Sciences Review and Research · 2024
    2. Combination Therapy with Oral Minoxidil and Dutasteride in the Treatment of Male Patterned Baldness: A Case Report Cosmoderma · 2022
    3. The Cost Effectiveness of Topical Minoxidil Therapy in the Management of Baldness The FASEB Journal · 2011
    4. Topical Minoxidil Does Little for Baldness Drug and Therapeutics Bulletin · 1989
    5. Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness Journal of The American Academy of Dermatology · 1987
    6. Dose-Response Study of Topical Minoxidil in Male Pattern Baldness Journal of The American Academy of Dermatology · 1986