A Retrospective Case-Control Study of Modifiable Risk Factors and Cutaneous Markers in Indian Patients with Young Coronary Artery Disease
June 2012
in “
JRSM Cardiovascular Disease
”
TLDR Young Indians with coronary artery disease often have risk factors like smoking and central obesity, and cutaneous markers should be monitored for lifestyle changes.
This retrospective case-control study conducted at a tertiary care center in India examined 292 patients aged 40 or younger with acute coronary artery disease (CAD) and 92 matched controls. The study found that dyslipidaemia (91%), smoking (74.3%), low high-density lipoprotein cholesterol (68.9%), central obesity (47.7%), and greying of hair (34.9%) were significant risk factors for premature CAD. Women showed a higher prevalence of dyslipidaemia, low HDL-C, central obesity, hypertension, diabetes, and family history of premature CAD compared to men. The presence of cutaneous markers was significantly associated with premature CAD, suggesting that clinicians should monitor these markers closely and encourage lifestyle modifications in at-risk patients.
