The Stendhalian Prison In 'The Red And The Black': A Happy Dungeon

January 2002 in “ Analecta malacitana: Revista de la Sección de Filología de la Facultad de Filosofía y Letras ”

Paul Brown

minoxidil androgenetic alopecia hypertrichosis topical treatment hair growth pharmacology mechanism of action clinical efficacy adverse events Rogaine

TLDR Minoxidil is a popular hair growth treatment, but how it works isn't fully understood.

Minoxidil was initially used as an antihypertensive medication, but its side effect of hypertrichosis led to its development as a topical treatment for hair growth. By 2002, it was the primary treatment for androgenetic alopecia and was also used off-label for other hair loss conditions. Although widely used, the precise mechanism by which minoxidil promotes hair growth was not fully understood. The article reviewed and updated information on the pharmacology, mechanism of action, clinical efficacy, and adverse events associated with topical minoxidil.

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Research cited in this study

5 / 5 results

research The Effect of Topical Minoxidil Treatment on Follicular Sulfotransferase Enzymatic Activity

4 citations , May 2019 in “PubMed”

Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

research Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil

4 citations , March 2017 in “PubMed”

Increasing the dosage of minoxidil can help hair regrowth in women who didn't respond to the standard treatment.

research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study

1 citations , July 2016 in “PubMed”

Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.

research The use of minoxidil to attempt to prevent alopecia during chemotherapy for gynecologic malignancies.

36 citations , January 1991 in “PubMed”

This pilot study tested the effect of 2% Minoxidil on preventing hair loss during chemotherapy for gynecologic cancers in 10 women. Each participant served as her own control, with only part of the scalp treated. Four patients were unevaluable due to non-compliance. Among the six evaluable patients, five experienced significant hair loss within four weeks of starting chemotherapy, while one had no hair loss in either treated or untreated areas. The study concluded that 2% Minoxidil was non-toxic but ineffective in preventing chemotherapy-induced alopecia.

research Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory

26 citations , April 1977 in “PubMed”

Minoxidil, a blood pressure drug, can cause excessive hair growth, but this can be successfully treated with a hair removal agent called calcium thioglycolate.

Similar Research

6 / 1000+ results

research Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

May 2023 in “Clinical, Cosmetic and Investigational Dermatology”

More personalized and effective treatments for androgenetic alopecia are needed.

research Minoxidil

January 2022 in “Springer eBooks”

research Consensus Recommendations for the Management of Androgenetic Alopecia in Egypt: A Modified Delphi Study

October 2025 in “Clinical Cosmetic and Investigational Dermatology”

Experts created guidelines for treating hair loss in Egypt, focusing on personalized care.

A Randomized, Investigator-Blinded, Controlled, Split-Scalp Study of the Efficacy and Safety of a 1550-nm Fractional Erbium-Glass Laser, Used in Combination with Topical 5% Minoxidil Versus 5% Minoxidil Alone, for the Treatment of Androgenetic Alopecia

research A Randomized, Investigator-Blinded, Controlled, Split-Scalp Study of the Efficacy and Safety of a 1550-nm Fractional Erbium-Glass Laser, Used in Combination with Topical 5% Minoxidil Versus 5% Minoxidil Alone, for the Treatment of Androgenetic Alopecia

29 citations , April 2019 in “Lasers in Medical Science”

Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.

research An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia

71 citations , January 2004 in “Dermatology”

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

research Melatonin in the Topical Treatment of Androgenetic Alopecia

4 citations , August 2011 in “Aktuelle Dermatologie”

Topical melatonin is a safe treatment that may reduce hair loss in people with androgenetic alopecia.

The Stendhalian Prison In 'The Red And The Black': A Happy Dungeon

Research cited in this study

research The Effect of Topical Minoxidil Treatment on Follicular Sulfotransferase Enzymatic Activity

research Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil

research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study

research The use of minoxidil to attempt to prevent alopecia during chemotherapy for gynecologic malignancies.

research Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory

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