Association of Eight Single Nucleotide Polymorphisms of Chromosomes 20 and X with Androgenetic Alopecia Among Ethnic Han Chinese from Yunnan

    June 2016 in “ PubMed ”
    Meng Ye, Zhi Yang, Mao Li, Yuming Xing, Faming Zeng, Baowen Cheng
    TLDR Certain genetic markers on chromosome 20 are linked to hair loss in the Han Chinese from Yunnan.
    The study investigated the association of 8 single nucleotide polymorphisms (SNPs) from chromosomes X and 20 with androgenetic alopecia in 115 cases and 125 controls among the ethnic Han population from Yunnan. The results showed no association with the 4 SNPs on the X chromosome. However, significant differences were found in the genotypic frequencies of rs2180439, rs913063, and rs1160312 between the groups, with the T allele of rs2180439 and A alleles of rs913063 and rs1160312 being more frequent in the alopecia group. The study concluded that these SNPs on chromosome 20 were associated with androgenetic alopecia in this population.
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