Association of Eight Single Nucleotide Polymorphisms of Chromosomes 20 and X with Androgenetic Alopecia Among Ethnic Han Chinese from Yunnan

The study investigated the association of 8 single nucleotide polymorphisms (SNPs) from chromosomes X and 20 with androgenetic alopecia in 115 cases and 125 controls among the ethnic Han population from Yunnan. The results showed no association with the 4 SNPs on the X chromosome. However, significant differences were found in the genotypic frequencies of rs2180439, rs913063, and rs1160312 between the groups, with the T allele of rs2180439 and A alleles of rs913063 and rs1160312 being more frequent in the alopecia group. The study concluded that these SNPs on chromosome 20 were associated with androgenetic alopecia in this population.