Genotypes of Single-Nucleotide Polymorphisms on DENND1A in Association with Polycystic Ovary Syndrome Among Saudi Arabian Females

    July 2025
    Hana Hakami, Saleh Alzahrani, Jawaher Al‐Zahrani … Maha H. Daghestani
    Studysummary This study reported a significant association between the SNP rs2479106 in the DENND1A gene and PCOS in Saudi Arabian females, while no association was found for SNPs rs10818854 and rs10986105.
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    Research cited in this study 6

    1. The Prevalence and Phenotypic Features of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis Human Reproduction · 2016
    2. Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update Reproductive Biology and Endocrinology · 2016
    3. Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan BMC Medicine · 2010
    4. Metabolic Features of the Reproductive Phenotypes of Polycystic Ovary Syndrome Human Reproduction Update · 2009
    5. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003
    6. Polycystic Ovary Syndrome: Clinical and Biochemical Features New England journal of medicine/˜The œNew England journal of medicine · 1995