TLDR Microbiota imbalances may contribute to acne and offer new treatment insights.
The document reviewed the complex pathogenesis of acne, highlighting its association with endocrine factors, abnormal keratosis of hair follicle sebaceous ducts, and microbial infection. It emphasized recent studies suggesting that dysregulation of the skin microbiome and intestinal microbiota might play roles in acne's pathophysiology. Additionally, it discussed research on traditional Chinese medicine (TCM) treatments for acne, considering the influence of these microbiota. The exact etiology and pathogenesis of acne remained unclear, but the involvement of microbiota offered new insights into potential therapeutic approaches.
8 citations
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March 2010 in “Chinese medical journal/Chinese Medical Journal” Malassezia infection may cause refractory acne, and antifungal treatments can help.
January 2022 in “Dermatology Review” Higher IL-31 levels are linked to worse itching in chronic kidney disease patients.
77 citations
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July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
47 citations
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September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.
22 citations
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October 2020 in “Anais Brasileiros de Dermatologia” The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.