Serum Interleukin 18 And NLRP3 In Patients With Alopecia Areata

    October 2024 in “ Benha Medical Journal ”
    Salma AwadAllah Al Yamani, Asmaa Mohamed Al Refaei, Eman H. Hassan, Nehad A. Fouad, Karem Taha Khalil
    TLDR Patients with Alopecia Areata have higher levels of certain inflammatory markers.
    This study investigated the levels of serum Interleukin-18 (IL-18) and NLRP3 in 50 patients with Alopecia Areata (AA) compared to 50 healthy controls. The results showed that both IL-18 and NLRP3 levels were significantly higher in patients with AA than in the control group, with a P-value of 0.01. This suggests a potential role of these inflammatory markers in the pathogenesis of AA, highlighting their importance in understanding the inflammatory processes involved in this condition.
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