Sequence of a Cashmere goat type I hair keratin gene and its expression in skin

December 2008 in “ Frontiers of Agriculture in China ”

Jun Yin, Jinquan Li, Yanjun Zhang, Changqing Li

type I hair keratin cDNA hair follicles keratin gene amino acid sequence in situ hybridization hair keratin gene expression hair structure

TLDR The Cashmere goat hair keratin gene is crucial for hair structure.

The study focused on the sequencing and expression analysis of a type I hair keratin gene from Cashmere goats. Researchers isolated and sequenced a cDNA from goat skin, identifying it as the goat hair keratin gHa1 cDNA. The 413 amino acid sequence showed a high homology of 97.8% with the Sheep 8C1 type I mRNA. In situ hybridization demonstrated strong expression of this keratin in the cortex of both primary and secondary hair follicles, indicating its significant role in hair structure.

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Research cited in this study

9 / 9 results

research The Catalog of Human Hair Keratins

272 citations , September 2001 in “Journal of Biological Chemistry”

Human hair keratins were cataloged, showing their roles in hair differentiation stages.

research The Catalog of Human Hair Keratins

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research Sequence and Expression of Murine Type I Hair Keratins mHa2 and mHa3

47 citations , June 1994 in “Experimental Cell Research”

research Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene

27 citations , November 1991 in “Journal of Investigative Dermatology”

research Differential Expression of Type I Hair Keratins

51 citations , March 1990 in “Journal of Investigative Dermatology”

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues

124 citations , December 1988 in “Differentiation”

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum)

187 citations , May 1988 in “Differentiation”

research The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins

198 citations , October 1986 in “Differentiation”

research Hair Keratin: Composition, Structure and Biogenesis

45 citations , January 1986

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10× Genomics Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber

research 10× Genomics Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber

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The study found specific skin cells and genes that may affect the quality of cashmere in Liaoning Cashmere Goats.

Sequence of a Cashmere goat type I hair keratin gene and its expression in skin

Research cited in this study

research The Catalog of Human Hair Keratins

research The Catalog of Human Hair Keratins

research Sequence and Expression of Murine Type I Hair Keratins mHa2 and mHa3

research Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene

research Differential Expression of Type I Hair Keratins

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum)

research The complement of native α-keratin polypeptides of hair-forming cells: A subset of eight polypeptides that differ from epithelial cytokeratins

research Hair Keratin: Composition, Structure and Biogenesis

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