Secondary Cutis Verticis Gyrata Induced by Long-Term Use of High-Dose Topical Minoxidil

    August 2024 in “ Skin Appendage Disorders ”
    Juste Baksanskaite, Natalia Caballero Uribe, Ralph M. Trüeb
    Studysummary This study presents the first reported case of cutis verticis gyrata resulting from long-term, high-concentration topical minoxidil use for treating male androgenetic alopecia, highlighting a potential link to insulin-like growth factor effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 16

    1. Serious Complication of Low-Dose Oral Minoxidil for Hair Loss JAAD case reports · 2022
    2. Pericardial, Pleural Effusion and Anasarca: A Rare Complication of Low-Dose Oral Minoxidil for Hair Loss JAAD case reports · 2022
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    5. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    6. Efficacy and Safety of a New 10% Topical Minoxidil Versus 5% Topical Minoxidil and Placebo in the Treatment of Male Androgenetic Alopecia: A Trichoscopic Evaluation Journal of Dermatological Treatment · 2019
    7. Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia Skin appendage disorders · 2017
    8. Cantú Syndrome Is Caused by Mutations in ABCC9 The American Journal of Human Genetics · 2012
    9. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    10. Pseudoacromegaly Induced by the Long-Term Use of Minoxidil Journal of The American Academy of Dermatology · 2003
    11. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    12. In the Absence of Streptomycin, Minoxidil Potentiates the Mitogenic Effects of Fetal Calf Serum, Insulin-Like Growth Factor 1, and Platelet-Derived Growth Factor on NIH 3T3 Fibroblasts in a K+ Channel-Dependent Fashion Journal of Investigative Dermatology · 1996
    13. Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts Archives of Dermatological Research · 1995
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    Related research 1

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023