Scarring Alopecia in Tumor Necrosis Factor-Alpha Antagonists-Induced Scalp Psoriasis

April 2023 in “ Journal of Psoriasis and Psoriatic Arthritis ”

Avital Baniel, A. Peled, Liat Samuelov, Valentina Zemser, Andrea Gat, Roni P. Dodiuk‐Gad, Michael Ziv, Wassim Azzam, Eran Zittan, Hagit Matz, Eli Sprecher, Mor Pavlovsky

scarring alopecia tumor necrosis factor-alpha TNFα inhibitors psoriatic alopecia scalp psoriasis TNF-alpha inhibitors

Studysummary This study found that TNFα inhibitors can induce psoriatic alopecia, highlighting that early diagnosis and discontinuation of the drugs in some cases may prevent irreversible scalp damage.

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research Psoriatic Alopecia in a Patient With Crohn's Disease: An Uncommon Manifestation of Tumor Necrosis Factor Alpha Inhibitors

April 2021 in “Cutis”

This study reports the case of a 12-year-old girl who developed psoriatic alopecia after increasing her dose of the TNF-α inhibitor adalimumab for Crohn's disease, emphasizing psoriatic alopecia as a phenomenon associated with these medications.

research Adalimumab-Induced Scalp Psoriasis with Severe Alopecia

13 citations , July 2019 in “Dermatologic therapy”

This case report describes a 37-year-old woman who developed scalp psoriasis and severe alopecia after taking adalimumab, with complete hair regrowth following treatment change.

research TNF-Inhibitor Associated Psoriatic Alopecia: Diagnostic Utility of Sebaceous Lobule Atrophy

20 citations , March 2017 in “Journal of cutaneous pathology”

This study describes tumor necrosis factor inhibitor-associated psoriatic alopecia, highlighting the distinctive histologic feature of sebaceous lobule atrophy, which is potentially reversible and helps differentiate it from idiopathic psoriatic alopecia.

research Adalimumab-Related Alopecia in a Patient Affected by Psoriasis

14 citations , January 2017 in “Dermatology Online Journal”

This case report describes a patient with psoriasis who developed alopecia with unique histological features after anti-TNF therapy, suggesting that such effects may require considering treatment suspension for severe cases.

research Tumor Necrosis Factor-Induced Alopecia: Alternative Pathology and Therapy

7 citations , January 2017 in “Dermatology Online Journal”

In this case report, the researchers described two women with Crohn disease who developed alopecia related to TNF inhibitor therapy, noting various histopathological features of drug-induced alopecia and treating it effectively with different therapeutic approaches.

research TNF Inhibitor Induced Alopecia: An Unusual Form of Psoriasiform Alopecia That Breaks the Renbök Mold

9 citations , January 2017 in “Dermatology Online Journal”

This study describes a distinctive hair loss pattern with features of psoriasis and alopecia areata linked to TNF-α inhibitors, noting various management options despite the lack of consensus guidelines.

research Alopecia Secondary to Anti-Tumor Necrosis Factor-Alpha Therapy

42 citations , March 2015 in “Anais Brasileiros de Dermatologia”

This study reports two cases of alopecia associated with anti-TNF therapy, highlighting a new entity combining features of alopecia areata and psoriatic alopecia.

research Adalimumab-Induced Psoriatic Alopecia/Alopecia Areata-Like Reaction in a Patient with Crohn's Disease

9 citations , January 2015 in “Dermatology Online Journal”

This case report describes a patient with Crohn's disease developing alopecia and psoriasiform skin lesions while on adalimumab treatment.

research Alopecia Universalis Successfully Treated With Adalimumab

37 citations , October 2014 in “JAMA dermatology”

This case report describes a woman with alopecia universalis, resistant to multiple treatments, who experienced successful hair regrowth with adalimumab, suggesting potential mechanisms for future investigation.

research Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature

49 citations , January 2012 in “Dermatology”

In this study, only 1 out of 5 patients with anti-TNF-α induced psoriasiform eruptions showed good response to topical treatment, while systemic therapy and discontinuation of anti-TNF-α may prevent scarring alopecia in severe cases.

Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia

research Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia

72 citations , February 2011 in “The American Journal of Dermatopathology”

This study found that anti-TNF therapy-induced alopecia exhibits distinct clinical and histopathological features and can mimic psoriatic alopecia and alopecia areata, with some patients improving with topical treatment.

research Development of Alopecia Areata Universalis in a Patient Receiving Adalimumab

69 citations , December 2006 in “Archives of dermatology”

This entry contains no research abstract, so no scientific findings or conclusions are reported.

research Recurrence of Alopecia Areata in a Patient Receiving Etanercept Injections

75 citations , June 2005 in “Archives of Dermatology”

In this case report, a patient experienced a recurrence of alopecia areata while undergoing etanercept treatment, suggesting the drug may not effectively prevent this condition's return.

research Cytokines and Growth Factors Influence Hair Growth In Vitro: Possible Implications for the Pathogenesis and Treatment of Alopecia Areata

91 citations , March 1996 in “Archives of Dermatological Research”

This study concluded that cytokines and growth factors significantly regulate hair growth in vitro, with some completely inhibiting growth, such as EGF and TNFα.