Response to Variables Affecting the Potential Efficacy of Platelet-Rich Plasma in Dermatology

    January 2021 in “ Journal of The American Academy of Dermatology ”
    Katerina Svigos, Lu Yin, Katharina S. Shaw, Daniel Gutierrez, Erik J. Peterson, Kristen Lo Sicco, Jerry Shapiro
    Image of study
    TLDR The authors concluded that PRP injections were not significantly effective for treating lichen planopilaris and its variants and should not be used as the only treatment.
    The authors of the document responded to Sharun et al.'s comments on their research letter regarding the use of platelet-rich plasma (PRP) in lichen planopilaris (LPP) and its variants. They provided additional details about their PRP protocol, which involves obtaining 8-16 mL of whole blood, centrifuging it to yield 5-10 mL of PRP, and administering 50-100 injections across the affected scalp. The authors agreed that variability in PRP procedures could affect efficacy and concluded that while koebnerization was not observed in their patient cohort, PRP injection therapy did not show a significant response in treating LPP and its variants. They did not recommend PRP as monotherapy for these conditions and emphasized the need for randomized controlled trials (RCTs) to truly assess the efficacy and safety of PRP injections in LPP and its variants, noting that current RCTs are mostly limited to androgenetic alopecia.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 79 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 month ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Why can't you drink caffeine after PRP?

      in Treatment  9 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  548 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

    Similar Research

    5 / 1000+ results