TLDR Women with PCOS have higher renin and d-dimer levels, especially if they have COVID-19.
This study investigated the levels of renin and d-dimer in 120 women, including 80 with polycystic ovarian syndrome (PCOS) and 40 without, with half of each group also having COVID-19. The results indicated that women with PCOS had significantly higher levels of renin and d-dimer compared to non-PCOS women. Additionally, PCOS patients exhibited increased levels of hormones, fasting blood glucose, and lipid profiles, while high-density lipoprotein and follicle-stimulating hormone levels were lower. Notably, PCOS patients with COVID-19 showed a significant increase in renin and d-dimer levels, suggesting a potential relationship between these biomarkers in PCOS patients with COVID-19.
3 citations
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September 2021 in “International Journal of Molecular Sciences” Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
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September 2018 in “Journal of Drug Delivery and Therapeutics” PCOS is a common hormonal disorder in women linked to several health risks and can be managed through various treatments.
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May 2021 in “Dermatologic Therapy” Possible link between androgens and COVID-19 severity; more research needed.