TLDR Recombinant goat VEGF164 speeds up hair growth in mice.
The study demonstrated that recombinant goat VEGF164 (rgVEGF164) increased hair growth in mice. Researchers cloned VEGF164 cDNA from Inner Mongolia cashmere goats into a prokaryotic expression vector and expressed it in E. coli BL21 cells. The rgVEGF164 protein was purified and identified using western blot analysis. When applied to the dorsal area of shaved mice, rgVEGF164 resulted in faster hair regrowth compared to the control group, indicating its potential to enhance hair growth.
35 citations
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October 2013 in “Journal of Dermatological Science” VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.
4 citations
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January 2013 in “Genetics and Molecular Research” VEGF and microvessel density are closely linked and peak during specific hair growth phases in cashmere goats.
23 citations
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June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
120 citations
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May 2012 in “Experimental Cell Research” VEGF promotes hair follicle cell growth through the VEGFR-2/ERK pathway.
56 citations
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June 2002 in “Biomaterials” Controlled release of VEGF in a collagen hydrogel boosts hair growth in mice.
520 citations
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February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
139 citations
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July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
