Complete In Vitro Regeneration of Hair and Skin Appendages Through Combined Effects of Cellular Organization and Mechanical Stimulation
January 2019
in “
Institutional Repositories DataBase (IRDB)
”
hair follicles cutaneous appendages erector muscle of hair in vitro processes cellular organization mechanical conditions three-layered gel micro-bead culture fetal mouse epidermal cells mouse ES cells cytokines C2C12 cells skeletal muscle myoblast cell line cellular orientation cyclic mechanical stimuli gel fibers cell-culture device cyclic stretching micro-scale mature myotubes hair follicle structures hair muscle muscle cells cell stretching
Studysummary This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.
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