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In this study, human hair follicle pluripotent stem cells transplanted into severed mouse sciatic nerves differentiated into Schwann cells and supported nerve regeneration, offering a promising alternative to embryonic or iPS cells for regenerative medicine.

This research describes a two-step culture system for pluripotent mouse ES cells that produces hair follicle-like structures, providing a valuable model to study stem cell differentiation in vitro.

This study found that transplanted ES cell-derived epidermal stem cells promoted the formation of epidermis, sweat gland-like, sebaceous gland-like, and hair follicle-like structures in mouse skin defects.

This study achieved regeneration of hair follicle-like structures and erector muscle of hair in vitro by simulating cellular organization and applying mechanical stimuli.

This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.