Quantitative Proteomic Analysis of Dermal Papilla from Male Androgenetic Alopecia Comparing Before and After Treatment with Low-Level Laser Therapy

    March 2019 in “ Lasers in Surgery and Medicine
    Ratchathorn Panchaprateep, Trairak Pisitkun, Nuttiya Kalpongnukul
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    TLDR Low-level laser therapy improves hair growth and dermal papilla cell function.
    This study analyzed the effects of low-level laser therapy (LLLT) on dermal papilla (DP) cells in male androgenetic alopecia (AGA). The researchers used quantitative proteomic analysis to compare the protein expression in DP cells before and after LLLT treatment. They found that LLLT increased the expression of several proteins related to hair growth and DP cell function. The study suggests that LLLT can be a beneficial therapeutic option for AGA. However, the study had a small number of subjects, and further investigations are needed to support the hypothesis.
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