May 2025 in “Aesthetic Plastic Surgery” 
August 2026 in “International Journal of Nanomedicine” This review highlights the potential of exosome-based therapies for androgenetic alopecia by modulating key signaling pathways in hair follicles, suggesting a promising treatment option that requires further research to validate long-term safety and efficacy.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that the multifunctional exosome-based delivery platform EX104 reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, performing comparably to minoxidil while also enhancing capillary growth and follicular proliferation.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This source reviews current research on using exosomes for treating alopecia and finds promising preclinical evidence, particularly with exosomes from dermal papilla and adipose-derived stem cells. However, it highlights significant gaps in clinical translation regarding safety, delivery, and mechanisms, suggesting more rigorous studies are needed.
October 2025 in “Gene Expression” This review explores the potential of exosomes, which contain substances that may stimulate hair follicle activity, as a new therapeutic strategy for alopecia, and discusses their possible benefits and risks based on current knowledge of microRNAs and intracellular signaling in hair follicle morphogenesis.
