Investigation of the Development of Hypersensitivity and Hyperalgesia After Repeated Application of Platelet-Rich Plasma in Rats: An Experimental Study

April 2019 in “ Aesthetic Surgery Journal ”

Bilsev İnce, Mehmet Yıldırım, İbrahim Kılınç, Pembe Oltulu, Mehmet Dadacı

platelet-rich plasma hyperalgesia nerve growth factor inflammatory mediators PRP NGF

Studysummary This study found that repeated applications of both nonactivated and activated PRP in rats led to increased hypersensitivity to pain, which may be linked to elevated nerve growth factor levels and inflammatory mediators.

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research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations , November 2017 in “Aesthetic Plastic Surgery”

In this study, researchers found that homologous PRP (h-PRP) significantly increased hair density more than both nonactivated (n-PRP) and activated (a-PRP) autologous PRP in patients with androgenetic alopecia, suggesting h-PRP as a potentially more effective treatment option for hair loss.