Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases

    February 2023 in “ Journal of Investigative Dermatology ”
    Hisato Iriki, Hayato Takahashi, Masayuki Amagai
    Studysummary OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
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    Research cited in this study 7

    1. Thymic Stromal Lymphopoietin in Cutaneous Immune-Mediated Diseases Frontiers in immunology · 2021
    2. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    3. Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing Its Impact on T Regulatory Cell and NK Cell Populations ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2020
    4. Regulatory T-Cells in Alopecia Areata Journal of cutaneous pathology · 2019
    5. The Microbiome in Patients with Atopic Dermatitis Journal of Allergy and Clinical Immunology · 2018
    6. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    7. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010

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