Primary Cicatricial Alopecia Among Libyan Patients: A Clinicopathological and Epidemiological Study

    Fauzia Musbah
    TLDR Early diagnosis and treatment can lessen the impact of cicatricial alopecia.
    The study focused on primary cicatricial alopecia among 31 Libyan patients, diagnosed through biopsy and tricoscopy between January 2018 and December 2019. It aimed to assess the epidemiological and clinicopathological characteristics of the condition. The results showed that 16.1% of patients had lichen planopilaris, 25.8% had discoid lupus erythematosus, 6% had folliculitis decalvans, 6.45% had pseudopelade of Brocq, and 16.12% had frontal fibrosing alopecia. The study concluded that cicatricial alopecia predominantly affected middle-aged individuals, especially females, and emphasized that early diagnosis and treatment could reduce the burden of the disease.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  99 upvotes 8 months ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 1 month ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 11 months ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

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