Prepubertal Fibrosing Alopecia in a Pattern Distribution

    March 2025 in “ International Journal of Trichology ”
    Nikollas Munhoz, Jivko Kamarachev, Ralph M. Trüeb
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    TLDR FAPD in children may not depend on androgens and should be treated with anti-inflammatory measures and minoxidil.
    The article discusses a case of prepubertal fibrosing alopecia in a pattern distribution (FAPD) in a 9-year-old girl, marking the first reported instance of FAPD in a child. This condition, characterized by hair thinning and histopathological features similar to lichen planopilaris (LPP), suggests that FAPD may not be androgen-dependent, as previously thought. The study highlights the importance of differentiating FAPD from other forms of alopecia and suggests that treatment should focus on anti-inflammatory measures combined with hair growth-promoting agents like minoxidil. The findings challenge the efficacy of 5-alpha reductase inhibitors for FAPD, given its potential androgen independence.
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