TLDR The argon gas-based cryotherapy effectively reduced keloid scars but caused some hypopigmentation and had a recurrence rate, especially in Afro-American patients.
This study evaluated the effectiveness of an argon gas-based intralesional cryotherapy system for treating keloid scars in 25 patients with 30 keloid scars, including all Fitzpatrick skin types, over a 1-year follow-up. The treatment resulted in a significant 62% reduction in scar volume, improved scar quality, and alleviated pain and itching. However, 17% of scars recurred, particularly in Afro-American patients, and hypopigmentation was a notable issue. The argon gas-based system proved effective, especially for scars previously unresponsive to liquid nitrogen-based cryotherapy.
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