Polycystic Ovary Syndrome - Increased Risk of Depression Development: Links and Risk Factors

    Julia SZYMAŃSKA, Kamil KAPŁON, Weronika PAWŁOCIK, Laura WOJTALA, Weronika PAWLAK, Dominika KOJDER, Izabela Kamińska, Ewa GRABOWSKA, Lena MUSIAŁ, Agnieszka MOŻDŻYŃSKA
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    TLDR Women with Polycystic Ovary Syndrome have a higher chance of getting depressed.
    Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting 6-10% of women in reproductive age, with symptoms including hyperandrogenism, ovulation disorders, infertility, overweight and obesity, and glucose-insulin homeostasis disorders. The study emphasizes a significant relationship between PCOS and depression, with a median incidence of depression in women with PCOS at 36.6%, compared to 14.2% in women without PCOS. The exact mechanism of this relationship is still unknown, but factors such as increased BMI, infertility, high cortisol levels, body image, vitamin D deficiency, and elevated inflammation markers may play a significant role.
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