Patient Validation of Estimation of Health Utility Values in Alopecia Areata

April 2025 in “ PharmacoEconomics - Open ”

Caleb Dixon, Thomas M Price, Elin Gruffydd, Andrew Lloyd, Ernest H. Law

Alopecia Areata health utility values disease burden AA

TLDR Patients with Alopecia Areata are willing to trade life duration for better quality of life.

The study investigates how patients with Alopecia Areata (AA) balance the trade-offs between the quantity of life and disease-specific quality of life. It reveals a high willingness among patients to trade off life duration, aligning with findings from a UK public study, which underscores the significant disease burden associated with AA.

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Research cited in this study

11 / 11 results

research Estimation of Health Utility Values for Alopecia Areata

4 citations , March 2024 in “Quality of Life Research”

More severe hair loss in alopecia areata greatly impacts patients and caregivers.

research Two Phase 3 Trials of Baricitinib for Alopecia Areata

148 citations , March 2022 in “The New England Journal of Medicine”

Baricitinib was effective in treating alopecia areata in two major trials.

research Validation of the Alopecia Areata Patient Priority Outcomes Questionnaire in Adults and Adolescents with Alopecia Areata

22 citations , November 2021 in “Dermatology and Therapy”

The AAPPO questionnaire is a reliable tool for assessing hair loss impact in alopecia areata patients.

research Patient Perspectives of the Social, Emotional and Functional Impact of Alopecia Areata: A Systematic Literature Review

67 citations , March 2021 in “Dermatology and Therapy”

Alopecia areata greatly harms quality of life, causing emotional and social issues.

research Development of the Alopecia Areata Patient Priority Outcomes Instrument: A Qualitative Study

11 citations , March 2021 in “Dermatology and therapy”

Researchers created a new tool to measure the effects of alopecia areata from the patient's view, focusing on hair loss, daily life, and emotional health.

research Treatment of Alopecia Areata: An Australian Expert Consensus Statement

95 citations , November 2018 in “Australasian journal of dermatology”

Alopecia areata treatment varies, with no optimal method established yet.

research Health-Related Quality of Life Among Patients With Alopecia Areata: A Systematic Review

95 citations , July 2016 in “Journal of The American Academy of Dermatology”

People with alopecia areata, a skin disease, generally have a poor quality of life, especially if more of their scalp is affected.

research Alopecia Areata and Health-Related Quality of Life: A Systematic Review and Meta-Analysis

128 citations , February 2016 in “British Journal of Dermatology”

Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.

research Epidemiology and Burden of Alopecia Areata: A Systematic Review

144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

research Quality of Life in Alopecia Areata: A Sample of Tunisian Patients

45 citations , January 2013 in “Dermatology Research and Practice”

Alopecia areata significantly worsens quality of life, suggesting a need for mental health support.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations , April 2012 in “British Journal of Dermatology”

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Related Community Posts Join

6 / 1000+ results

community Lost 65% of hair last 3 years. No regrowth. Also have Seborrheic Dermatitis flare ups. Diagnosed by derm as "alopecia". Started taking 2 supplements I researched and 0 flare up for over 2 months. New hair growing. Scalp healthy. Everything else has stayed the same! Overjoyed is an understatement!!

in Treatment 18 upvotes 2 years ago

After suffering from hair loss and Seborrheic Dermatitis for three years with no improvement from various treatments, the individual found success with COQ10 and PQQ supplements, which led to new hair growth and a healthy scalp without flare-ups. They also plan to start additional supplements recommended by a dermatologist.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 11 upvotes 3 years ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Dutasteride has been nuking me

in Finasteride/Dutasteride 156 upvotes 4 months ago

The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.

community 22F. Should I even bother getting a biopsy? Is there any point?

6 upvotes 9 years ago

A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 2 years ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

Related Research

1 / 1 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.