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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

    Research

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      community Switching to Oral from Topical min effective or not

      in Minoxidil  6 upvotes 1 month ago
      Switching from topical to oral minoxidil may lead to better results for some users, with oral minoxidil generally being more effective due to higher absorption. However, it can also cause side effects like hypertrichosis and blood pressure issues, and individual responses may vary.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  410 upvotes 1 month ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  107 upvotes 2 months ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

      community This is what some balding dudes are like

      in Satire  1047 upvotes 6 months ago
      Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 9 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.