Effects of Oxidative Stress Prevention Using DNA Aptamer (Aptamin C) in Keratinocyte

January 2021 in “ Clinical Dermatology Open Access Journal ”

Sooho Choi

Aptamin C DNA aptamer vitamin C collagen synthesis antioxidant reactive oxygen species ROS anti-inflammatory keratinocyte Vitamin C

Studysummary This study observed that the Aptamin C® and vitamin C complex had effective ROS-scavenging and anti-inflammatory effects on human skin in both in vitro and clinical tests. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the effects of Aptamin C®, a DNA aptamer designed to enhance the antioxidant efficacy of vitamin C by preventing its oxidation. Vitamin C is known for its role in collagen synthesis and as a major antioxidant, but its effectiveness is often reduced due to oxidation. The research included both in vitro and clinical tests, which demonstrated that the Aptamin C® and vitamin C complex effectively scavenged reactive oxygen species (ROS) and exhibited anti-inflammatory properties, suggesting its potential benefits for human skin.

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