Effect of Low-Dose Finasteride on Serum PSA Concentrations

February 2007 in “ Journal watch ”

Robert Dreicer, FACP. FACP.

finasteride type II 5α-reductase inhibitor PSA prostate-specific antigen Propecia

Studysummary Low-dose finasteride lowers PSA levels, which can make prostate cancer harder to detect.

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Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

research Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial

89 citations , December 2006 in “Lancet Oncology”

In this study, 1 mg/day finasteride lowered serum PSA concentration in men aged 40–60, suggesting that PSA adjustment recommendations for prostate cancer screening using 5 mg/day finasteride should also apply to this lower dose for hair loss treatment.