New Proprietary Brands: Gabapentin
October 2004
in “
Australian Prescriber
”
TLDR Lifestyle changes are more effective than metformin for reducing type 2 diabetes risk.
The document discussed the management of hirsutism and the associated long-term risks, particularly focusing on insulin resistance and its link to metabolic syndrome and cardiovascular disease. It noted that while medications like flutamide and finasteride were not widely used in Australia due to potential side effects, such as hepatotoxicity and teratogenicity, there were no long-term clinical studies on the benefits of metformin for cardiovascular outcomes in women with polycystic ovary syndrome. The findings from the Diabetes Prevention Program Research Group indicated that lifestyle changes were more effective than metformin in reducing the incidence of type 2 diabetes, suggesting that clinicians should emphasize lifestyle modifications to reduce body mass and improve insulin sensitivity.