Evaluation of Patellar Tendon Structural Changes Following Biological Treatments: Secondary Analysis of Double-Blinded Clinical Trial of Bone Marrow Mesenchymal Stromal Cells and Leukocyte-Poor Platelet-Rich Plasma

In this study, the authors observed that the combined treatment group showed a significant increase in inflammatory cell density and a higher maximum tensile breaking force in tendon repair by the end of the second month.

This review explores how platelet- and marrow-derived biologics like PRP and BMAC exhibit both regenerative and antimicrobial properties useful in musculoskeletal conditions and wound healing, though their clinical outcomes are affected by preparation inconsistencies and lack of standardized protocols.

This review outlines the use of quantitative imaging techniques in monitoring tendon response to platelet-rich plasma treatment for chronic tendinopathy and reports that these methods may aid in tailoring PRP protocols.

This study suggests that platelet-rich plasma may improve pain and function in patients with partial-thickness rotator cuff tears and tendinopathy short-term, but the long-term benefits are unclear.

This review describes and compares the efficacy of bioregenerative therapies, specifically mesenchymal stem cells and platelet-rich plasma, for treating osteoarthritis, suggesting they may offer a less invasive and more effective alternative to surgery and conventional therapies.